Pathogenesis of renal failure in cirrhosis and fulminant hepatic failure. Issue 598 (August 1975)

• Record Type: Journal Article
• Authors: Wilkinson, S. P.; Hurst, D.; Portmann, B.; Williams, Roger
• Is Part Of: Postgraduate medical journal. Volume 51:Issue 598(1975)
• Page Start: 503
• Page End: 505
• Publication Date: 1975-08
• Subjects: Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.51.598.503
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : Acute renal failure in cirrhosis and fulminant hepatic failure represents a spectrum with 'functional renal failure' at one end and acute tubular necrosis at the other. In fulminant hepatic failure the development of renal failure is not necessarily a measure of the severity of liver damage. Functional renal failure is due to active renal vasoconstriction which may, at least in fulminant hepatic failure, be initiated by systemic endotoxaemia.