Parental age, genetic mutation, and cerebral palsy. Issue 1 (January 1993)

• Record Type: Journal Article
• Authors: Fletcher, N A; Foley, J
• Is Part Of: Journal of medical genetics. Volume 30:Issue 1(1993)
• Page Start: 44
• Page End: 46
• Publication Date: 1993-01
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.30.1.44
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : Parental age and birth order were studied in 251 patients with cerebral palsy. No parental age or birth order effects were observed in spastic quadriplegia or diplegia, but a paternal age effect was detected in those with athetoid/dystonic cerebral palsy and congenital hemiplegia. These observations indicate that some cases of athetoid/dystonic or hemiplegic cerebral palsy might arise by fresh dominant genetic mutation.