Ocular inflammatory changes in established multiple sclerosis. Issue 12 (December 1989)

• Record Type: Journal Article
• Authors: Graham, E M; Francis, D A; Sanders, M D; Rudge, P
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 52:Issue 12(1989)
• Page Start: 1360
• Page End: 1363
• Publication Date: 1989-12
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.52.12.1360
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Fifty consecutive patients with clinically definite multiple sclerosis were studied to assess the prevalence of concomitant uveitis. Asymptomatic ocular inflammatory changes were found in nine patients (18%) and appeared to show a positive correlation with severe and progressive disease. Conversely uveitis was uncommon in the presence of established optic atrophy which suggests a negative influence on its pathogenesis. In the absence of optic atrophy inflammatory changes in the eye may be a valuable index of disease activity.