Polycythaemia rubra vera and hairy cell leukaemia in the same patient: studies on the spleen. Issue 12 (December 1982)

• Record Type: Journal Article
• Authors: Mufti, GJ; Hamblin, TJ; Stevenson, FK; Fitchett, M
• Is Part Of: Journal of clinical pathology. Volume 35:Issue 12(1982)
• Page Start: 1312
• Page End: 1315
• Publication Date: 1982-12
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.35.12.1312
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : The first association of polycythaemia rubra vera (PRV) and hairy cell leukaemia (HCL) is reported. The secretion by spleen cells in short term culture of IfGλ to the exclusion κ demonstrated that despite aberrant surface marker studies the HCL was a monoclonal tumour of B cells. Chromosomal studies on splenic cells were not able to demonstrate the common clonal origin of the two tumours.