Changes in the gastric mucosa of the mouse associated with long lasting unsurmountable histamine H2 blockade. Issue 11 (November 1986)
- Record Type:
- Journal Article
- Title:
- Changes in the gastric mucosa of the mouse associated with long lasting unsurmountable histamine H2 blockade. Issue 11 (November 1986)
- Main Title:
- Changes in the gastric mucosa of the mouse associated with long lasting unsurmountable histamine H2 blockade.
- Authors:
- Poynter, D
Selway, S A
Papworth, S A
Riches, S R - Abstract:
- Abstract : The oral administration of loxtidine to mice at doses of 600, 250, and 50 mg/kg/day for 746 days produced carcinoid tumours of the gastric fundus. The fundic mucosa also showed marked atypical hyperplasia with changes in foveolar cells similar to those seen in early incomplete metaplasia. These effects may be related to the prolonged achlorhydria produced by this potent unsurmountable histamine H2 receptor antagonist.
- Is Part Of:
- Gut. Volume 27:Issue 11(1986)
- Journal:
- Gut
- Issue:
- Volume 27:Issue 11(1986)
- Issue Display:
- Volume 27, Issue 11 (1986)
- Year:
- 1986
- Volume:
- 27
- Issue:
- 11
- Issue Sort Value:
- 1986-0027-0011-0000
- Page Start:
- 1338
- Page End:
- 1346
- Publication Date:
- 1986-11
- Subjects:
- Gastroenterology -- Periodicals
616.33 - Journal URLs:
- http://gut.bmjjournals.com ↗
http://www.bmj.com/archive ↗ - DOI:
- 10.1136/gut.27.11.1338 ↗
- Languages:
- English
- ISSNs:
- 0017-5749
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 23675.xml