Diffuse encephalitic toxoplasmosis in HIV. Issue 3 (18th March 2021)

• Record Type: Journal Article
• Authors: Pearce, Jasmine; Sheridan, Ray; Shaw, Johnathan; Senior, Thomas
• Is Part Of: BMJ case reports. Volume 14:Issue 3(2021)
• Publication Date: 2021-03-18
• Subjects: infectious diseases -- neurology -- infection (neurology); Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2020-237456
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : This case demonstrates an atypical radiological presentation of cerebral toxoplasmosis in a 62-year-old HIV-positive patient. The diagnosis is discussed alongside MRI imaging, laboratory results and treatment. Central nervous system toxoplasmosis is typically associated with ring enhancing lesions on neuroimaging with contrast, but the radiology for this patient shows diffuse white matter changes and ependymal enhancement, which would normally suggest an alternative diagnosis.