Non-invasive method for early diagnosis of herpes simplex encephalitis. Issue 12 (December 1988)

• Record Type: Journal Article
• Authors: Hanada, N; Kido, S; Terashima, M; Nishikawa, K; Morishima, T
• Is Part Of: Archives of disease in childhood. Volume 63:Issue 12(1988)
• Page Start: 1470
• Page End: 1473
• Publication Date: 1988-12
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.63.12.1470
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : For the early diagnosis of herpes simplex encephalitis IgG and IgM antibodies to herpes simplex virus in cerebrospinal fluid were measured by an enzyme linked immunosorbent assay (ELISA) and a local production index was calculated. Using these three criteria, 31 cases of various neurological illnesses were analysed. All eight cases of herpes simplex encephalitis were diagnosed correctly in the acute phase, and there were no false positive results.