Clinical evaluation of clobetasone butyrate eye drops in the treatment of anterior uveitis and its effects on intraocular pressure. Issue 9 (September 1981)

• Record Type: Journal Article
• Authors: Eilon, L A; Walker, S R
• Is Part Of: British journal of ophthalmology. Volume 65:Issue 9(1981)
• Page Start: 644
• Page End: 647
• Publication Date: 1981-09
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.65.9.644
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Clobetasone butyrate has been formulated as a new steroid preparation of use in ophthalmology and has been compared with prednisolone phosphate and betamethasone phosphate in the treatment of anterior uveitis. The results from 4 double-blind, between-patient studies have shown that all 3 treatments are effective in reducing the signs and symptoms of this intraocular disease. 87% of those patients receiving clobetasone butyrate had a good or satisfactory response, but no differences in therapeutic efficacy were observed between these 3 steroid treatments. Clobetasone butyrate had little effect on intraocular pressure when compared with dexamethasone or hydrocortisone, both of which cause a significant rise in intraocular pressure.