Nocturnal decrease in vasopressin secretion into plasma in patients with multiple system atrophy. Issue 4 (1st October 1999)

• Record Type: Journal Article
• Authors: Ozawa, Tetsutaro; Tanaka, Hajime; Nakano, Ryoichi; Sato, Masahisa; Inuzuka, Takashi; Soma, Yoshiaki; Yoshimura, Naoko; Fukuhara, Nobuyoshi; Tsuji, Shoji
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 67:Issue 4(1999)
• Page Start: 542
• Page End: 545
• Publication Date: 1999-10-01
• Subjects: arginine-vasopressin -- circadian rhythm -- multiple system atrophy -- autonomic failure -- nocturnal polyuria; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.67.4.542
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : To determine whether the nocturnal decrease in arginine vasopressin (AVP) secretion into the plasma, found in a patient with multiple system atrophy (MSA) reported previously, is a usual finding in MSA, the plasma AVP concentrations in 13 patients with MSA were measured every 4 hours during a 24 hour period. The plasma AVP concentrations in these patients showed significant daily variations and were the lowest during the night. This finding indicates that patients with MSA often exhibit nocturnal decrease in AVP secretion into the plasma. The results suggest the possibility that the system responsible for the daily variations in AVP secretion is involved in MSA.