Mechanisms in open-angle glaucoma. Issue 5 (May 1978)

• Record Type: Journal Article
• Authors: Mapstone, R
• Is Part Of: British journal of ophthalmology. Volume 62:Issue 5(1978)
• Page Start: 275
• Page End: 282
• Publication Date: 1978-05
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.62.5.275
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : One hundred and nineteen eyes from 68 patients with open-angle glaucoma were provoked by means of a pilocarpine phenylephrine provocative test. In 22% the response was the same as that seen in normal eyes. In 78% the response was the same as that seen in contralateral eyes at risk to the development of closed-angle glaucoma, which do not develop a positive provocative test. The 68 patients were randomised and 34 submitted to a "dummy" provocative test. No significant change in pressure or outflow occurred. Fifty-two of the 93 eyes with an abnormal provocative test were selected for a peripheral iridectomy and reprovoked at least 6 months after operation. The results were significantly different from those obtained before operation. It was concluded that partial-angle closure could be demonstrated in some eyes with apparent open-angle glaucoma. The mechanisms involved in the production of partial-angle closure in eyes with apparent open-angle glaucoma are discussed.