An unexpected cause of muscle pain in diabetes. Issue 4 (1st April 2001)

• Record Type: Journal Article
• Authors: Silberstein, L; Britton, K E; Marsh, F P; Raftery, M J; D'Cruz, D
• Is Part Of: Annals of the rheumatic diseases. Volume 60:Issue 4(2001)
• Page Start: 310
• Page End: 312
• Publication Date: 2001-04-01
• Subjects: diabetes mellitus -- diabetic muscle infarction -- technetium-99m sestamibi scan; Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/ard.60.4.310
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Diabetic muscle infarction is a rare condition which may present to a rheumatologist. It was first reported in 1965. Two illustrative cases are described here and the mechanisms of pathogenesis discussed. Analysis of the published data, results of the muscle biopsies, and a technetium-99m sestamibi scan suggest that the condition, which occurs against a background of diabetic microangiopathy, can be triggered by an ischaemic event and causes extensive muscle necrosis through hypoxia-reperfusion injury and compartment syndrome.