Infantile osteopetrosis; bone marrow transplantation from a cousin donor. Issue 5 (November 1995)

• Record Type: Journal Article
• Authors: Taylor, G M; Dearden, S P; Will, A M; Evans, D I; Stevens, R F; Simon, S; Super, M; Morrell, G; Fergusson, W D; Brown, I H
• Is Part Of: Archives of disease in childhood. Volume 73:Issue 5(1995)
• Page Start: 453
• Page End: 455
• Publication Date: 1995-11
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.73.5.453
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : The successful correction of infantile osteopetrosis in an Asian child by bone marrow transplantation (BMT) from an HLA-A, B matched cousin donor is reported. Retrospective HLA molecular analysis revealed that patient and donor were incompatible for HLA-DPB1. Donor type cells detected in the patient after transplantation indicate successful engraftment. The patient is currently alive and well.