Somatostatin therapy of acute experimental pancreatitis. Issue 9 (September 1977)

• Record Type: Journal Article
• Authors: Lankisch, P G; Koop, H; Winckler, K; Fölsch, U R; Creutzfeldt, W
• Is Part Of: Gut. Volume 18:Issue 9(1977)
• Page Start: 713
• Page End: 716
• Publication Date: 1977-09
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.18.9.713
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Because somatostatin (SRIF) reduces exocrine pancreatic secretion, its effect on acute pancreatitis was investigated in rats. Linear SRIF reduced serum amylase and lipase but had no effect on pancreatic necrosis, oedema, leucocyte infiltration, and enzyme content. The mortality rate was not reduced. These results do not recommend the use of SRIF in the treatment of acute pancreatitis.