Plasma intestinal alkaline phosphatase and intermediate molecular mass gamma glutamyltransferase activities in the differential diagnosis of jaundice. Issue 10 (October 1987)

• Record Type: Journal Article
• Authors: Collins, D; Goold, M F; Rosalki, S B; Mayne, P D; Foo, A Y
• Is Part Of: Journal of clinical pathology. Volume 40:Issue 10(1987)
• Page Start: 1252
• Page End: 1255
• Publication Date: 1987-10
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.40.10.1252
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : An assessment was made of the value of: (i) the demonstration of intestinal alkaline phosphatase in plasma for the differentiation of intrahepatic from post-hepatic jaundice in 122 jaundiced patients; and (ii) the demonstration of an intermediate molecular mass gamma glutamyltransferase in plasma for the identification of post-hepatic cholestasis in 74 jaundiced patients. The first test had a diagnostic sensitivity of only 32% with a specificity of 86%; the second test had a sensitivity of 50% and specificity of 75%. It is concluded that neither procedure is worth while.