Indices of intact serum parathyroid hormone and renal excretion of calcium, phosphate, and magnesium. Issue 11 (November 1990)

• Record Type: Journal Article
• Authors: Shaw, N J; Wheeldon, J; Brocklebank, J T
• Is Part Of: Archives of disease in childhood. Volume 65:Issue 11(1990)
• Page Start: 1208
• Page End: 1211
• Publication Date: 1990-11
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.65.11.1208
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Up to date reference ranges were established for fasting renal excretion of calcium, phosphorus, and magnesium on 101 healthy children aged 2-15 years. A normal range for intact parathyroid hormone was also measured. The indices of calcium and magnesium excretion showed no correlation with age or sex so that a common range for all children could be established. The 97th centile values for urinary calcium:creatinine and magnesium:creatinine ratios were 0.69 mmol:mmol and 1.05 mmol:mmol respectively. The calculated tubular maximum for phosphate/litre of glomerular filtrate (TmPO4/GFR) showed no correlation with age with a geometric mean value of 1.67 mmol/l. The normal range for intact serum parathyroid hormone for the age group was 11-35 ng/l, which is lower than the adult normal range using the same assay. There was an inverse correlation between TmPO4/GFR and intact parathyroid hormone in this group of normal children.