Biopsy findings in cases of rejection of liver allograft. Issue 12 (December 1985)

• Record Type: Journal Article
• Authors: Hubscher, S G; Clements, D; Elias, E; McMaster, P
• Is Part Of: Journal of clinical pathology. Volume 38:Issue 12(1985)
• Page Start: 1366
• Page End: 1373
• Publication Date: 1985-12
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.38.12.1366
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : Features of rejection were found in 21 needle biopsies obtained from seven patients after liver transplantation. Wedge biopsies taken peroperatively were used as a baseline for comparison. Rejection was diagnosed by excluding other known causes of graft dysfunction using appropriate methods. In cases in which these criteria were fulfilled a consistent picture of rejection was seen, and this was useful in clinical management. Two features constantly present in cases of acute rejection were: a dense mixed portal inflammatory infiltrate; and polymorphonuclear infiltration of biliary epithelium.