Biotin-labelled antigen screening test for toxoplasma IgM antibody. Issue 2 (February 1989)

• Record Type: Journal Article
• Authors: Joss, A W; Skinner, L J; Moir, I L; Chatterton, J M; Williams, H; Ho-Yen, D O
• Is Part Of: Journal of clinical pathology. Volume 42:Issue 2(1989)
• Page Start: 206
• Page End: 209
• Publication Date: 1989-02
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.42.2.206
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : A method for the simple preparation of biotin-labelled toxoplasma antigen was used with avidin peroxidase in an IgM-capture enzyme linked immunosorbent assay (BAM-ELISA). Although the overall predictive value of a positive result was only 38%, its low cost and 100% sensitivity makes it a very suitable screening test. Positive results can be confirmed by an alternative assay, thus providing a more economical and effective diagnostic service than either screening all sera by a commercial test or selecting sera for IgM testing.