Yttrium-90 therapy and 99MTc pertechnetate knee uptake measurements in the management of rheumatoid arthritis. Issue 2 (April 1983)

• Record Type: Journal Article
• Authors: Kyle, V; Hazleman, B L; Wraight, E P
• Is Part Of: Annals of the rheumatic diseases. Volume 42:Issue 2(1983)
• Page Start: 132
• Page End: 137
• Publication Date: 1983-04
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/ard.42.2.132
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Twenty-eight knees with chronic arthritis and effusion were treated with intra-articular 90Y. Synovial activity was assessed by measuring 99mTc pertechnetate uptake. There was a significant difference in uptake between controls and patients. Those who had a good response to 90Y (15 patients) showed a significant decrease in uptake, not seen in those who failed to respond. The pattern of 90Y distribution was examined and appeared to correspond to areas of increased synovial activity; these patterns and their significance have not been previously reported. Factors which could help to predict response to 90Y are discussed.