Electroencephalographic Abnormalities and 5-Year Outcome in First-Episode Psychosis. (May 2014)

• Record Type: Journal Article
• Authors: Manchanda, Rahul; Norman, Ross; Malla, Ashok; Harricharan, Rajendra; Northcott, Sandra; Richard, Julie
• Is Part Of: Canadian journal of psychiatry =. Volume 59:Number 5(2014)
• Page Start: 285
• Page End: 288
• Publication Date: 2014-05
• Subjects: first-episode psychosis -- electroencephalogram -- electroencephalography -- outcome -- schizophrenia -- longitudinal studies; Psychiatry -- Periodicals; Psychiatry -- Canada -- Periodicals; 616.8900971
• DOI: 10.1177/070674371405900508
• Languages: English
• ISSNs: 0706-7437

Abstract

Objective: To examine the relation of electroencephalographic abnormalities to 5-year outcomes in first-episode psychosis (FEP). Methods: Patients ( n = 103) had their baseline electroencephalogram (EEG) classified by modified Mayo Clinic criteria. Symptoms and psychosocial functioning were rated after 5 years of treatment. Results: Dysrhythmic EEG was associated with persistence in positive and negative symptoms of psychoses and poorer psychosocial functioning at 5-year follow-up, independently of other characteristics, such as duration of untreated illness or premorbid adjustment. A higher percentage of people with comorbid substance use disorder had normal EEG. Conclusions: Abnormal baseline EEG in FEP is associated with poorer 5-year symptomatic and functional outcome.