Regional cerebral blood flow by SPECT imaging in Sturge-Weber disease: an aid for diagnosis. Issue 12 (December 1989)

• Record Type: Journal Article
• Authors: Chiron, C; Raynaud, C; Tzourio, N; Diebler, C; Dulac, O; Zilbovicius, M; Syrota, A
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 52:Issue 12(1989)
• Page Start: 1402
• Page End: 1409
• Publication Date: 1989-12
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.52.12.1402
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Regional cerebral blood flow (rCBF) was studied using SPECT (single photon emission computed tomography) with 133-Xenon in 13 patients with confirmed Sturge-Weber disease, aged 9 months to 18 years. CT scan, performed at the same time, showed evident cerebral angioma in 10 but not in three. A marked hypoperfused area was found in all patients, ranging from -32% to -72% and of the same location as the CT signs. The hypoperfusion seems to result from post ictal phenomenon as well as from chronic ischaemia. SPECT imaging is therefore a sensitive method for visualising intracranial angioma in Sturge-Weber disease and it provides an aid for diagnosis when a CT scan is not reliable.