Postprandial gastro-oesophageal reflux in healthy people. Issue 9 (September 1977)

• Record Type: Journal Article
• Authors: Kaye, M D
• Is Part Of: Gut. Volume 18:Issue 9(1977)
• Page Start: 709
• Page End: 712
• Publication Date: 1977-09
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.18.9.709
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Distal oesophageal pH was monitored for three hours after a standard meal in 10 young healthy subjects without symptoms of gastro-oesophageal reflux. Episodes of reflux occurred in nine of these subjects; and, in five, oesophageal pH was less than 5 for between 11 and 75% of the first postprandial hour. Intermittent incompetence of the lower oesophageal sphincter after food must, therefore, be regarded as a normal phenomenon. The method described would be suitable for the evaluation of agents believed to weaken or to strengthen the lower oesophageal sphincter.