Familial syndrome with panhypopituitarism, hypoplasia of the hypophysis, and poorly developed sella turcica. Issue 8 (August 1978)

• Record Type: Journal Article
• Authors: Sipponen, P; Similä, S; Collan, Y; Autere, T; Herva, R
• Is Part Of: Archives of disease in childhood. Volume 53:Issue 8(1978)
• Page Start: 664
• Page End: 667
• Publication Date: 1978-08
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.53.8.664
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Two sisters who died at the age of 2.5 years and 5 weeks are described. Both showed signs of panhypopituitarism. At necropsy, no hypophysis could be found in the first child and a rudimentary and partly ectopic hypophysis was found in the other. Both children had a flat, poorly developed sella turcica, and the sellar anomaly could be seen in skull x-rays. These patients represent a hereditary syndrome characterised by neonatal panhypopituitarism, hypoplasia of the pituitary gland, and flat sella turcica.