Vigabatrin in the treatment of epilepsy: a long-term follow-up study. Issue 4 (April 1989)

• Record Type: Journal Article
• Authors: Tartara, A; Manni, R; Galimberti, C A; Mumford, J P; Iudice, A; Perucca, E
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 52:Issue 4(1989)
• Page Start: 467
• Page End: 471
• Publication Date: 1989-04
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.52.4.467
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Twenty-five adult epileptic patients who had shown a satisfactory clinical response to add-on vigabatrin under placebo-controlled conditions continued on long-term treatment for up to 47 months (median 22 months). The initially favourable therapeutic response was generally maintained throughout the observation period with an overall good clinical tolerance. No evidence of neurotoxicity was detected by multimodal evoked potentials monitoring.