Trigeminal neuropathy with nasal ulceration: report of two cases and one necropsy. Issue 2 (February 1976)

• Record Type: Journal Article
• Authors: Spillane, J D; Urich, H
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 39:Issue 2(1976)
• Page Start: 105
• Page End: 113
• Publication Date: 1976-02
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.39.2.105
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Two cases are reported of progressive trigeminal neutopathy with nasal ulceration. One patient developed signs of spinal cord involvement 15 years after the onset of trigeminal symptoms and died after a total course of 21 years. Necropsy revealed an unusual trigeminospinal system degeneration with deposition of amyloid-like substances in the affected structures. The other patient is alive eight years after the onset of symptoms, the only indication of a lesion outside the trigeminal nerve being a patch of numbness in one leg.