Azobenzene-modified antisense oligonucleotides for site-specific cleavage of RNA with photocontrollable property. Issue 96 (29th September 2016)
- Record Type:
- Journal Article
- Title:
- Azobenzene-modified antisense oligonucleotides for site-specific cleavage of RNA with photocontrollable property. Issue 96 (29th September 2016)
- Main Title:
- Azobenzene-modified antisense oligonucleotides for site-specific cleavage of RNA with photocontrollable property
- Authors:
- Wang, Xingyu
Liang, Xingguo - Abstract:
- Abstract : Photoresponsive azobenzene-modified antisense oligonucleotides for site-specific RNA cleavage by RNase H. Abstract : We presented a RNase H-based strategy for site-specific RNA cleavage using azobenzene-modified antisense oligonucleotides (ASO). The results showed that RNase H can bind to the ASO–RNA heteroduplex, and cut the RNA strand at predetermined sites. Moreover, cleavage rate can be regulated by photoirradiation, with a 5-fold photomodulation efficiency at most.
- Is Part Of:
- RSC advances. Volume 6:Issue 96(2016)
- Journal:
- RSC advances
- Issue:
- Volume 6:Issue 96(2016)
- Issue Display:
- Volume 6, Issue 96 (2016)
- Year:
- 2016
- Volume:
- 6
- Issue:
- 96
- Issue Sort Value:
- 2016-0006-0096-0000
- Page Start:
- 93398
- Page End:
- 93402
- Publication Date:
- 2016-09-29
- Subjects:
- Chemistry -- Periodicals
540.5 - Journal URLs:
- http://pubs.rsc.org/en/Journals/JournalIssues/RA ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6ra20954h ↗
- Languages:
- English
- ISSNs:
- 2046-2069
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8036.750300
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 23628.xml