Hypothalamo-pituitary-adrenal function in intrinsic non-atopic asthma. Issue 5 (October 1975)

• Record Type: Journal Article
• Authors: Collins, J V; Bellamy, D; Britton, M G; Townsend, J; Brown, D J
• Is Part Of: Thorax. Volume 30:Issue 5(1975)
• Page Start: 578
• Page End: 581
• Publication Date: 1975-10
• Subjects: Chest -- Diseases -- Periodicals; Thorax; Chest -- Diseases; Periodicals; Periodicals; 617.54
• DOI: 10.1136/thx.30.5.578
• Languages: English
• ISSNs: 0040-6376

Abstract

Abstract : Sixteen patients with intrinsic non-atopic asthma with persistent wheezing who had never been treated with corticosteroids showed normal adrenocortical responses to prolonged stimulation with Tetracosactin Depot. In a subgroup of six patients the hypothalamo-pituitary-adrenal (HPA) response to a standard insulin stress test was normal. It is concluded that impaired responsiveness of the HPA axis is unlikely to be a common factor in initiating or maintaining airways obstruction in patients with intrinsic asthma.