Comparative trial of 2 weeks and 8 weeks cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood. Issue 4 (April 1973)

• Record Type: Journal Article
• Authors: Barratt, T. M.; Cameron, J. S.; Chantler, C.; Ogg, C. S.; Soothill, J. F.
• Is Part Of: Archives of disease in childhood. Volume 48:Issue 4(1973)
• Page Start: 286
• Page End: 290
• Publication Date: 1973-04
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.48.4.286
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : A comparative trial of 2 weeks and 8 weeks cyclophosphamide therapy given during steroid-maintained remission in 32 children with steroid-sensitive relapsing nephrotic syndrome of childhood is reported. A significantly greater number of the 16 children who received 2 weeks therapy relapsed after steroid withdrawal than of those who received 8 weeks therapy. Relapses occurred later after 2 weeks cyclophosphamide therapy than in our previous experience of steroid treatment alone.