Anatomy and White Matter Connections of the Superior Parietal Lobule. Issue 3 (10th July 2021)

• Record Type: Journal Article
• Authors: Lin, Yueh-Hsin; Dadario, Nicholas B; Hormovas, Jorge; Young, Isabella M; Briggs, Robert G; MacKenzie, Alana E; Palejwala, Ali H; Fonseka, R Dineth; Kim, Sihyong J; Tanglay, Onur; Fletcher, Luke R; Abraham, Carol J; Conner, Andrew K; O'Donoghue, Daniel L; Sughrue, Michael E
• Is Part Of: Operative neurosurgery. Volume 21:Issue 3(2021)
• Page Start: E199
• Page End: E214
• Publication Date: 2021-07-10
• Subjects: Superior parietal lobule -- SPL -- DSI -- Anatomy -- Tractography -- White matter; Nervous system -- Surgery -- Periodicals; 617.480590
• DOI: 10.1093/ons/opab174
• Languages: English
• ISSNs: 2332-4252

Abstract

Abstract: BACKGROUND: The superior parietal lobule (SPL) is involved in somatosensory and visuospatial integration with additional roles in attention, written language, and working memory. A detailed understanding of the exact location and nature of associated white matter tracts could improve surgical decisions and subsequent postoperative morbidity related to surgery in and around this gyrus. OBJECTIVE: To characterize the fiber tracts of the SPL based on relationships to other well-known neuroanatomic structures through diffusion spectrum imaging (DSI)-based fiber tracking validated by gross anatomical dissection as ground truth. METHODS: Neuroimaging data of 10 healthy, adult control subjects was obtained from a publicly accessible database published in Human Connectome Project for subsequent tractographic analyses. White matter tracts were mapped between both cerebral hemispheres, and a lateralization index was calculated based on resultant tract volumes. Post-mortem dissections of 10 cadavers identified the location of major tracts and validated our tractography results based on qualitative visual agreement. RESULTS: We identified 9 major connections of the SPL: U-fiber, superior longitudinal fasciculus, inferior longitudinal fasciculus, inferior fronto-occipital fasciculus, middle longitudinal fasciculus, extreme capsule, vertical occipital fasciculus, cingulum, and corpus callosum. There was no significant fiber lateralization detected. CONCLUSION: The SPL is an important region implicated in a variety of tasks involving visuomotor and visuospatial integration. Improved understanding of the fiber bundle anatomy elucidated in this study can provide invaluable information for surgical treatment decisions related to this region.