Effects of naftidrofuryl on breathlessness and exercise tolerance in chronic bronchitis. Issue 8 (August 1982)

• Record Type: Journal Article
• Authors: Williams, A J; Osman, J; Skinner, C
• Is Part Of: Thorax. Volume 37:Issue 8(1982)
• Page Start: 617
• Page End: 619
• Publication Date: 1982-08
• Subjects: Chest -- Diseases -- Periodicals; Thorax; Chest -- Diseases; Periodicals; Periodicals; 617.54
• DOI: 10.1136/thx.37.8.617
• Languages: English
• ISSNs: 0040-6376

Abstract

Abstract : Naftidrofuryl enhances oxidative phosphorylation and might therefore be expected to improve exercise tolerance and breathlessness in advanced chronic bronchitis. This hypothesis was tested in a four-week placebo-controlled trial in 11 bronchitic patients. Seven patients completed the study. There was no evidence of any benefit from naftidrofuryl either subjectively or after a 12-minute walking test.