Organophosphates and monocyte esterase deficiency. Issue 8 (August 1995)

• Record Type: Journal Article
• Authors: McClean, E; Mackey, H; Markey, G M; Morris, T C
• Is Part Of: Journal of clinical pathology. Volume 48:Issue 8(1995)
• Page Start: 768
• Page End: 770
• Publication Date: 1995-08
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.48.8.768
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : AIMS--To examine the possibility that monocyte esterase deficiency (MED) could be caused by exposure to organophosphates. METHODS--Pseudocholinesterase, paraoxonase and arylesterase activities were measured in the serum and acetylcholinesterase activity was measured in the red cells of a group of monocyte esterase deficient subjects and compared with the enzyme activities of a control group of monocyte esterase positive subjects. RESULTS--No significant difference was found between the enzyme activities of the monocyte esterase deficient group and the control group for any of the esterases investigated. CONCLUSION--Current or recent exposure to organophosphorus is not the cause of MED.