Increased serum CA 19-9 antibodies in Sjögren's syndrome. Issue 875 (September 1998)

• Record Type: Journal Article
• Authors: Safadi, R.; Ligumsky, M.; Goldin, E.; Ilan, Y.; Haviv, Y. S.; Nusair, S.
• Is Part Of: Postgraduate medical journal. Volume 74:Issue 875(1998)
• Page Start: 543
• Page End: 544
• Publication Date: 1998-09
• Subjects: Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.74.875.543
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : A 67-year-old woman with a history of thyroiditis presented with recent intermittent epigastric pain and nausea. Hyperamylasaemia, oedema of the pancreas, and high serum levels of lipase and CA 19-9 were found. Xerostomia and dry eyes developed later, accompanied by an abnormal Schirmer's test. The diagnosis of Sjögren's syndrome was confirmed by increased anti-Ro and anti-La antibodies and the histological findings of parotid gland biopsy. Two additional cases of Sjögren's syndrome with elevated serum CA 19-9 are also described. These observations of elevated serum lipase and serum CA 19-9 in Sjögren's syndrome without evidence of malignancy may reflect pancreatic involvement in this disorder.