Beta-blockers, lipoproteins and non-insulin dependent diabetes. Issue 758 (December 1988)

• Record Type: Journal Article
• Authors: Feher, M. D.; Rains, S. G.; Richmond, W.; Torrens, D.; Wilson, G.; Wadsworth, J.; Sever, P. S.; Elkeles, R. S.
• Is Part Of: Postgraduate medical journal. Volume 64:Issue 758(1988)
• Page Start: 926
• Page End: 930
• Publication Date: 1988-12
• Subjects: Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.64.758.926
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : In a study on 138 hypertensive non-insulin dependent diabetic subjects, factors influencing lipoproteins were assessed. Multiple regression analyses were carried out in order to assess the influence of beta-blocker antihypertensive therapy while making allowances for other confounding variables. In males, but not in females, on a beta-blocker for hypertension, total high density lipoprotein- (HDL-) and HDL-subfraction cholesterol were significantly lower while the serum triglyceride was increased, though not significantly. In male non-insulin dependent diabetics, regimens containing a beta-blocker may worsen an already abnormal lipoprotein profile and antihypertensive agents other than beta-blocking agents should be used if possible.