Advanced micro/nanomotors for enhanced bioadhesion and tissue penetration. (June 2021)

• Record Type: Journal Article
• Authors: Lv, Jinyang; Xing, Yi; Xu, Tailin; Zhang, Xueji; Du, Xin
• Is Part Of: Applied materials today. Volume 23(2021)
• Publication Date: 2021-06
• Subjects: Micro/nanomotors -- Enhanced bioadhesion -- Deep tissue penetration -- Tissue perforation -- Disease therapy; Materials science -- Periodicals; Materials -- Research -- Periodicals; 620.1105
• DOI: 10.1016/j.apmt.2021.101034
• Languages: English
• ISSNs: 2352-9407

Abstract

Highlights: Micro/nanomotors are capable of converting different forms of energy into autonomous motion. Micro/nanomotors can enhance bioadhesion and tissue penetration due to autonomous motion. Micro/nanomotors can improve the therapeutic effect in the treatment of cancer and other diseases. This review highlights recent prospects in the enhanced bioadhesion and tissue penetration. Abstract: Micro/nanomotors (MNMs) can significantly enhance bioadhesion and tissue penetration due to their ability of autonomous motion compared with traditional passive cargo delivery carriers. Subsequently, the rapid internalization of the MNMs into cells and tissue leads to more efficient delivery and release of the loaded cargos into target sites, thus significantly improving the therapeutic effect in the treatment of cancer and other diseases. This review highlights the recent prospects about advanced MNMs for the enhanced bioadhesion and tissue penetration. Graphical abstract: Micro/nanomotors (MNMs) with self-propelled movement characteristic can enhance bioadhesion and tissue penetration in the treatment of cancer and other diseases, thus leading to more efficient delivery and release of the loaded cargos into target sites for improved therapeutic effect. Image, graphical abstract