Impact of cardiovascular comorbidity on increased neutrophil-lymphocyte ratio in pseudoexfoliation syndrome. Issue 28 (15th July 2022)

• Record Type: Journal Article
• Authors: Oh, Hea Young; Lee, Mee Yon; Lee, Young Chun; Shin, Hye-Young
• Is Part Of: Medicine. Volume 101:Issue 28(2022)
• Page Start: e29602
• Publication Date: 2022-07-15
• Subjects: cardiovascular comorbidity -- cardiovascular disease -- neutrophil-lymphocyte ratio -- pseudoexfolation syndrome; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000029602
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract : Background: The purpose of this study was to compare neutrophil-to-lymphocyte ratios (NLRs) of patients with pseudoexfoliation syndrome (PEX) according to the presence of cardiovascular disease (CVD) with those without CVD as controls. Methods: A total of 197 participants (97 patients with PEX and 100 participants without PEX regarded as the control group) were included in this retrospective study. The PEX group was divided into 2 subgroups, PEX with CVD (group 1) and PEX without CVD (group 2). NLRs were then compared to those of the control group. Results: The incidence of CVD was significantly ( P = .015) higher in the PEX group than in the control group. NLR was significantly higher in the group 1 and group 2 compared with that of the control group ( P = .048 and P = .002, respectively). In the PEX group, group 1 showed higher NLR than group 2 ( P = .023). Conclusion: Although the PEX group showed a higher incidence of CVD, the NLR was higher in the PEX group regardless of cardiovascular comorbidity than that in the control group.