The OGTT is highly reproducible in Africans for the diagnosis of diabetes: Implications for treatment and protocol design. (December 2020)

• Record Type: Journal Article
• Authors: Jagannathan, Ram; DuBose, Christopher W.; Mabundo, Lilian S.; Chung, Stephanie T.; Ha, Joon; Sherman, Arthur; Bergman, Michael; Sumner, Anne E.
• Is Part Of: Diabetes research and clinical practice. Volume 170(2020)
• Publication Date: 2020-12
• Subjects: Diabetes -- Africans -- OGTT -- Fasting plasma glucose; Diabetes -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462
• DOI: 10.1016/j.diabres.2020.108523
• Languages: English
• ISSNs: 0168-8227

Abstract

Abstract: Whether an OGTT reproducibly detects either type 2 diabetes (T2D) or prediabetes in Africans in unknown. Therefore, 131 Africans had two OGTT. Diagnostic reproducibility for T2D was excellent (κ = 0.84), but only moderate for prediabetes (κ = 0.51). A single OGTT positive for T2D may be sufficient to guide clinical care and inform epidemiologic study design. ClinicalTrials.gov Identifier: NCT00001853.