A 'NAC' for targeting proteins to the ER. Issue 9 (September 2022)
- Record Type:
- Journal Article
- Title:
- A 'NAC' for targeting proteins to the ER. Issue 9 (September 2022)
- Main Title:
- A 'NAC' for targeting proteins to the ER
- Authors:
- Coelho, João P.L.
Shao, Sichen - Abstract:
- Abstract : The signal recognition particle (SRP) cotranslationally targets a large and diverse portion of the nascent proteome to the endoplasmic reticulum (ER). A recent study by Jomaa et al. reveals an unexpected function for the ribosome-bound nascent chain-associated complex (NAC) in sensing ER-targeting signals and recruiting SRP to the appropriate ribosomes for high-fidelity targeting.
- Is Part Of:
- Trends in biochemical sciences. Volume 47:Issue 9(2022)
- Journal:
- Trends in biochemical sciences
- Issue:
- Volume 47:Issue 9(2022)
- Issue Display:
- Volume 47, Issue 9 (2022)
- Year:
- 2022
- Volume:
- 47
- Issue:
- 9
- Issue Sort Value:
- 2022-0047-0009-0000
- Page Start:
- 730
- Page End:
- 731
- Publication Date:
- 2022-09
- Subjects:
- Biochemistry -- Periodicals
572 - Journal URLs:
- http://www.sciencedirect.com/science/journal/09680004 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.tibs.2022.04.007 ↗
- Languages:
- English
- ISSNs:
- 0968-0004
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 9049.546000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 23562.xml