Herbal medicine treatment for patients with chronic subdural hematoma: A systematic review and meta-analysis. (May 2021)

• Record Type: Journal Article
• Authors: Kwon, Seungwon; Jin, Chul; Chung, Minho; Lee, JiEun; Cho, Seung-Yeon; Park, Seong-Uk; Jung, Woo-Sang; Moon, Sang-Kwan; Park, Jung-Mi; Ko, Chang-Nam; Cho, Ki-Ho
• Is Part Of: Complementary therapies in clinical practice. Volume 43(2021)
• Publication Date: 2021-05
• Subjects: Burr hole surgery -- Chronic subdural hematoma -- Herbal medicine -- Meta-analysis -- Systematic review; Integrative medicine -- Periodicals; Integrative medicine -- Research -- Periodicals; Alternative medicine -- Periodicals; 615.5
• DOI: 10.1016/j.ctcp.2021.101307
• Languages: English
• ISSNs: 1744-3881

Abstract

Abstract: Background and purpose: In Asian countries, herbal medicines have been used to treat Chronic subdural hematoma (CSDH) as an adjunctive therapy. This review aims to evaluate the efficacy and safety of herbal medicine on treating CSDH and preventing recurrent CSDH. Methods: A literature search was conducted on PubMed, CENTRAL, Scopus, CiNii, KTKP, NDSL, OASIS, and CNKI for randomized controlled trials that evaluated the effects of herbal medicines on CSDH. Results: Seven studies (n = 646) were included. The overall methodological quality of these studies was low. In the herbal group, the meta-analysis indicated statistically significant improvements in the total effective rate and recurrence rate as compared with those in the non-herbal group. Herbal treatments were found to be relatively safe. Conclusion: Herbal medicines might be efficacious in the management of CSDH and prevent its recurrence. Further rigorous studies will have to be conducted in order to make more definite conclusions. Highlights: This review evaluated efficacy and safety of herbal medicine on treating chronic subdural hematoma. Seven studies were included in meta-analysis. The methodological quality was low. Herbal group revealed significant improvements compared with non-herbal group. Herbal medicine might be efficacious in the management without side effects. Further rigorous studies will have to be conducted.