Nanoparticles: Nanoparticles Mimicking Viral Surface Topography for Enhanced Cellular Delivery (Adv. Mater. 43/2013). (18th November 2013)

• Record Type: Journal Article
• Authors: Niu, Yuting; Yu, Meihua; Hartono, Sandy B.; Yang, Jie; Xu, Hongyi; Zhang, Hongwei; Zhang, Jun; Zou, Jin; Dexter, Annette; Gu, Wenyi; Yu, Chengzhong
• Is Part Of: Advanced materials. Volume 25:Number 43(2013)
• Page Start: 6232
• Page End: 6232
• Publication Date: 2013-11-18
• Subjects: biomimetic synthesis -- drug delivery -- nanoparticles -- surface topography; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201370274
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : A new strategy to synthesize nanoparticles with enhanced cellular delivery efficiency is presented by Chengzhong Yu and co‐workers on page 6233. Silica nanoparticles mimicking virus surface topography exhibit increased cellular uptake performance and improved binding capacity towards biomolecules (e.g., genetic molecules, proteins); thus the cellular delivery performance can be improved. This understanding is important in the rational design of new cellular delivery vectors for a range of bioapplications.