Developmental defects of enamel and dental caries in the primary dentition: A systematic review and meta-analysis. (May 2017)

• Record Type: Journal Article
• Authors: Costa, Francine S.; Silveira, Ethieli R.; Pinto, Gabriela S.; Nascimento, Gustavo G.; Thomson, William Murray; Demarco, Flávio F.
• Is Part Of: Journal of dentistry. Volume 60(2017:May)
• Page Start: 1
• Page End: 7
• Publication Date: 2017-05
• Subjects: Developmental defects of enamel -- Dental caries -- Primary dentition -- Deciduous teeth -- Pediatric dentistry; Dentistry -- Periodicals; Dentistry -- Periodicals; Dentisterie -- Périodiques; Electronic journals; 617.6005
• DOI: 10.1016/j.jdent.2017.03.006
• Languages: English
• ISSNs: 0300-5712

Abstract

Abstract: Objectives: This systematic review and meta-analysis evaluated the association between developmental defects of enamel and dental caries in the primary dentition. Sources: Electronic searches were performed in PubMed, Web of Knowledge, Scopus and Scielo for the identification of relevant studies. Study selection: Observational studies that examined the association between developmental defects of enamel and dental caries in the deciduous dentition were included. Additionally, meta-analysis, funnel plots and sensitivity analysis were employed to synthesize the available evidence. Multivariable meta-regression analysis was performed to explore heterogeneity among studies. Data: A total of 318 articles were identified in the electronic searches. Of those, 16 studies were included in the meta-analysis. Pooled estimates revealed that children with developmental defects of enamel had higher odds of having dental caries (OR 3.32; 95%CI 2.41–4.57), with high heterogeneity between studies (I 2 80%). Methodological characteristic of the studies, such as where it was conducted, the examined teeth and the quality of the study explained about 30% of the variability. Concerning type of defect, children with hypoplasia and diffuse opacities had higher odds of having dental caries (OR 4.28; 95%CI 2.24–8.15; OR1.42; 95%CI 1.15–1.76, respectively). Conclusions: This systematic review and meta -analysis demonstrates a clear association between developmental defects of enamel and dental caries in the primary dentition.