Detection of pepsin in sputum: a rapid and objective measure of airways reflux. Issue 1 (5th November 2015)

• Record Type: Journal Article
• Authors: Strugala, Vicki; Woodcock, Andrew D.; Dettmar, Peter W.; Faruqi, Shoaib; Morice, Alyn H.
• Is Part Of: European respiratory journal. Volume 47:Issue 1(2016)
• Page Start: 339
• Page End: 341
• Publication Date: 2015-11-05
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.00827-2015
• Languages: English
• ISSNs: 0903-1936

Abstract

The diagnostic test, Peptest (RD Biomed Ltd, Cottingham, UK), detects pepsin in expectorated saliva and is established as a simple, noninvasive measure of reflux of gastric contents. It has been used to detect pepsin A in patients with both gastro-oesophageal reflux disease (GORD) and extra-oesophageal reflux into the laryngopharynx and airways [1–5]. Detection of salivary pepsin (Peptest) may be a useful adjunct in the diagnosis of airway reflux http://ow.ly/T7B0l