Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder. (27th April 2015)

• Record Type: Journal Article
• Authors: Mansueto, Pasquale; Seidita, Aurelio; Vitale, Giustina; Gangemi, Sebastiano; Iaria, Chiara; Cascio, Antonio
• Other Names: Teta Daniel Academic Editor.
• Is Part Of: BioMed research international. Volume 2015(2015)
• Publication Date: 2015-04-27
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2015/735615
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D deficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects.