Correlation Between Apparent Diffusion Coefficient Values of the Renal Parenchyma and Estimated Glomerular Filtration Rates on 3-T Diffusion-Weighted Echo-Planar Magnetic Resonance Imaging. Issue 5 (September 2019)

• Record Type: Journal Article
• Authors: Thiravit, Shanigarn; Suwanchatree, Paphatsanan; Skulratanasak, Peenida; Thiravit, Phakphoom; Suvannarerg, Voraparee
• Is Part Of: Journal of computer assisted tomography. Volume 43:Issue 5(2019)
• Publication Date: 2019-09
• Subjects: apparent diffusion coefficient -- chronic kidney disease -- diffusion magnetic resonance imaging -- glomerular filtration rate; Tomography -- Periodicals; Tomography -- Periodicals; Tomography; Periodicals; 616.0757
• DOI: 10.1097/RCT.0000000000000890
• Languages: English
• ISSNs: 0363-8715

Abstract

Abstract : Objective: To evaluate the relationship between the apparent diffusion coefficient (ADC) values of renal parenchyma and estimated glomerular filtration rates (eGFR). Methods: Data on 216 patients examined by 3-T magnetic resonance imaging for various reasons were retrospectively collected. Results: There was a significant linear correlation between the ADC values and eGFRs ( r = 0.254, P < 0.001). The ADC values in patients with an eGFR of less than 60 mL/min per 1.73 m 2 were significantly lower than those with an eGFR of 60 mL/min per 1.73 m 2 or greater. The mean ADC value of patients with grouped stage 2 disease was significantly higher than those with grouped stage 3 of chronic kidney disease ( P < 0.01). Conclusions: The ADC value of renal parenchyma may be a promising marker for the determination of patients with normal to mild reduction in renal function (eGFR ≥60 mL/min per 1.73 m 2 ) versus those with a moderate to severe reduction in renal function (eGFR <60 mL/min per 1.73 m 2 ).