Severe Leukemoid Reaction in a Case of Soft Tissue Sarcoma: A Case Report. Issue 4 (October 2019)

• Record Type: Journal Article
• Authors: Xing, Zhiqing; Scott, Brandon
• Is Part Of: JBJS case connector. Volume 9:Issue 4(2019)
• Publication Date: 2019-10
• Subjects: Orthopedic surgery -- Case studies -- Periodicals; Orthopedic surgery -- Periodicals; Orthopedics; Orthopedic Procedures; Orthopedic surgery; Periodicals; Electronic journals; Case studies; Periodicals; 616.7
• DOI: 10.2106/JBJS.CC.18.00368
• Languages: English
• ISSNs: 2160-3251

Abstract

Abstract : Case: A 62-year-old woman presented with severe leukocytosis and systemic symptoms including fatigue, low appetite, and weight loss. After 4 months of evaluation by doctors with extensive laboratory tests and imaging studies, a soft tissue sarcoma in the left posterior distal thigh was revealed. Quickly after surgical excision of the soft tissue sarcoma, the leukocytosis and systemic symptoms were dramatically resolved. Conclusions: Leukemoid reaction can present as a paraneoplastic syndrome. Awareness of soft tissue sarcoma as a possible cause of leukemoid reaction may help improve the early diagnosis and subsequent early intervention in future cases.