Effect of green tea on glycemic control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Issue 1 (January 2021)

• Record Type: Journal Article
• Authors: Asbaghi, Omid; Fouladvand, Faezeh; Gonzalez, Michael J.; Ashtary-Larky, Damoon; Choghakhori, Razieh; Abbasnezhad, Amir
• Is Part Of: Diabetes & metabolic syndrome. Volume 15:Issue 1(2021)
• Page Start: 23
• Page End: 31
• Publication Date: 2021-01
• Subjects: Fasting plasma glucose -- Insulin -- Hemoglobin A1c -- HOMA-IR -- Green tea -- Type 2 diabetes -- meta-Analysis; Diabetes -- Periodicals; Metabolism -- Disorders -- Periodicals; Diabetes Mellitus -- Periodicals; Metabolic Diseases -- Periodicals; Diabète -- Périodiques; Métabolisme, Troubles du -- Périodiques; Endocrinologie -- Périodiques; Diabète -- Physiopathologie -- Périodiques; Diabetes; Metabolism -- Disorders; Electronic journals; Periodicals; 616.462
• DOI: 10.1016/j.dsx.2020.11.004
• Languages: English
• ISSNs: 1871-4021

Abstract

Abstract: Background and aims: Several studies have investigated the potential beneficial effects of green tea in patients with type 2 diabetes mellitus (T2DM). Therefore, we aimed to perform a systematic review and meta-analysis of the randomized controlled trials (RCTs) that assessed the effect of supplementary intake of green tea on fasting plasma glucose (FPG), fasting insulin, hemoglobin A1c (HbA1c) and HOMA-IR in patients with T2DM. Methods: A systematic search was performed in Web of Science, PubMed and Scopus without any language and time restriction up to June 2019, to retrieve the related RCTs. Meta-analysis was carried out using both the random and fixed effects model where appropriate. I2 index was used to evaluate the heterogeneity. Results: Initial search yielded 780 publications. Fourteen articles were eligible. Our meta-analysis indicated that the supplementary intake of green tea had no significant effect on FPG, fasting insulin, HbA1c and HOMA-IR in patients with T2DM. Conclusion: Results of the present systematic review and meta-analysis indicated that the supplementary intake of green tea had no significant effect on FPG, fasting insulin, HbA1c and HOMA-IR in patients with T2DM. Highlights: Green tea had no significant effect on fasting plasma glucose, fasting insulin and HbA1c in patients with T2DM. Green tea had no significant effect on HOMA-IR in patients with T2DM. Further studies are needed to determine the effects of short- and long-term intake of green tea on glycemic control.