Catalyst free one-pot synthesis of α-aminophosphonates in aqueous ethyl lactate. (27th May 2019)

• Record Type: Journal Article
• Authors: Gao, Ge; Chen, Meng-Nan; Mo, Li-Ping; Zhang, Zhan-Hui
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 194:Number 4/6(2019)
• Page Start: 528
• Page End: 532
• Publication Date: 2019-05-27
• Subjects: α-Aminophosphonates -- three-component reaction -- ethyl lactate -- ultrasound; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2018.1542395
• Languages: English
• ISSNs: 1042-6507

Abstract

Abstract: An highly efficient and environmentally friendly process for the synthesis of α-aminophosphonates has been devised, through a one-pot three-component condensation of various aldehydes, amines and triethyl phosphate in water-ethyl lactate under ultrasonic irradiation conditions at room temperature. The expected products were obtained in high yield without the need for any additional catalyst. Graphical Abstract: UF0001