Recent Experiences and Advances in Contrast-Enhanced Subharmonic Ultrasound. (18th May 2015)

• Record Type: Journal Article
• Authors: Eisenbrey, John R.; Sridharan, Anush; Liu, Ji-Bin; Forsberg, Flemming
• Other Names: Xu Hui-Xiong Academic Editor.
• Is Part Of: BioMed research international. Volume 2015(2015)
• Publication Date: 2015-05-18
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2015/640397
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Nonlinear contrast-enhanced ultrasound imaging schemes strive to suppress tissue signals in order to better visualize nonlinear signals from blood-pooling ultrasound contrast agents. Because tissue does not generate a subharmonic response (i.e., signal at half the transmit frequency), subharmonic imaging has been proposed as a method for isolating ultrasound microbubble signals while suppressing surrounding tissue signals. In this paper, we summarize recent advances in the use of subharmonic imaging in vivo . These advances include the implementation of subharmonic imaging on linear and curvilinear arrays, intravascular probes, and three-dimensional probes for breast, renal, liver, plaque, and tumor imaging.