Accessing p‐Hydroxycinnamic Acids: Chemical Synthesis, Biomass Recovery, or Engineered Microbial Production?. Issue 1 (28th October 2020)

• Record Type: Journal Article
• Authors: Flourat, Amandine L.; Combes, Jeanne; Bailly‐Maitre‐Grand, Claire; Magnien, Kévin; Haudrechy, Arnaud; Renault, Jean‐Hugues; Allais, Florent
• Is Part Of: ChemSusChem. Volume 14:Issue 1(2021)
• Page Start: 118
• Page End: 129
• Publication Date: 2020-10-28
• Subjects: caffeic acid -- coumaric acid -- ferulic acid -- p-hydroxycinnamic acid -- sinapic acid; Green chemistry -- Periodicals; Sustainable engineering -- Periodicals; Chemistry -- Periodicals; Chemical engineering -- Periodicals; 660
• DOI: 10.1002/cssc.202002141
• Languages: English
• ISSNs: 1864-5631

Abstract

Abstract: p ‐Hydroxycinnamic acids (i. e., p‐ coumaric, ferulic, sinapic, and caffeic acids) are phenolic compounds involved in the biosynthesis pathway of lignin. These naturally occurring molecules not only exhibit numerous attractive properties, such as antioxidant, anti‐UV, and anticancer activities, but they also have been used as building blocks for the synthesis of tailored monomers and functional additives for the food/feed, cosmetic, and plastics sectors. Despite their numerous high value‐added applications, the sourcing of p ‐hydroxycinnamic acids is not ensured at the industrial scale except for ferulic acid, and their production cost remains too high for commodity applications. These compounds can be either chemically synthesized or extracted from lignocellulosic biomass, and recently their production through bioconversion emerged. Herein the different strategies described in the literature to produce these valuable molecules are discussed. Abstract : Make a choice : p ‐Hydroxycinnamic acids are of wide interest for various markets. Currently, their availability remains limited. Herein, an overview of the different strategies for (1) their synthesis through eco‐compatible process, (2) their extraction from agricultural co‐product, and (3) their bioproduction, is given and discussed.