Kikuchi-Fujimoto Disease: A Differential for When It is Not Systemic Lupus Erythematosus. (9th August 2022)

• Record Type: Journal Article
• Authors: Kazmi, Taskeen R.; Greear, Emma L.; Lavallee, Catherine A.; Stump, Michael S.; Bankole, Adegbenga A.
• Other Names: Hsu Tsai Ching Academic Editor.
• Is Part Of: Case reports in rheumatology. Volume 2022(2022)
• Publication Date: 2022-08-09
• Subjects: Rheumatology -- Periodicals; Rheumatology -- Case studies -- Periodicals; Rheumatic Diseases; Connective Tissue Diseases; Rheumatology; Periodicals; Electronic journals; Case studies; Periodicals; 616.723
• DOI: 10.1155/2022/7709246
• Languages: English
• ISSNs: 2090-6889

Abstract

Abstract : Kikuchi-Fujimoto disease (KFD) is a rare and benign disease process that is characterized by fever and lymphadenopathy that was first described in young Japanese women in the early 1970s. Knowledge of KFD is important as it can often mimic other causes of lymphadenopathy including systemic lupus erythematosus (SLE) or malignancies, and this can lead to invasive diagnostic testing and even treatments that can be avoided. The etiology and exact mechanism by which KFD develops is not fully understood at this time, but is thought to be an immune response of T cells and histiocytes to viral or bacterial infections. We present a 35-year-old African-American woman who was referred to the rheumatology clinic by our colleagues in the breast clinic with new onset right axillary lymphadenopathy and abnormal serologic testing with the suspicion of SLE after a malignancy had been ruled out.