Diagnostics of Thyroid Malignancy and Indications for Surgery in the Elderly and Younger Counterparts: Comparison of 3, 749 Patients. (16th October 2017)

• Record Type: Journal Article
• Authors: Kaliszewski, Krzysztof; Diakowska, Dorota; Strutyńska-Karpińska, Marta; Wojtczak, Beata; Aporowicz, Michał; Forkasiewicz, Zdzisław; Balcerzak, Waldemar; Łukieńczuk, Tadeusz; Domosławski, Paweł
• Other Names: Selek Ugur Academic Editor.
• Is Part Of: BioMed research international. Volume 2017(2017)
• Publication Date: 2017-10-16
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2017/1012451
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Background . It seems valuable for clinicians to know if diagnostics of thyroid malignancy (TM) and indications for surgery in the elderly patients differ from these in younger counterparts. Materials and Methods . Retrospective analysis of the medical records of 3, 749 patients surgically treated for thyroid tumor. Data of patients with histopathology confirmed TM (n = 309 ) were studied. Results. The rate of cytological prediction to malignancy was more than three times higher in elderly women. Compression was a main reason for surgery in the elderly (p < 0.0001 ). The final diagnosis of malignancy was significantly higher in older women (p = 0.002 ). Clinical suspicion of malignancy was positively correlated with histopathological diagnosis in total group of women (r = 0.543, p < 0.001 ) and total group of men (r = 0.560, p < 0.001 ). The subgroup of the eldest TM patients included a significantly higher number of subjects with advanced cancer and primary tumor progression (p < 0.0001 ). Distant metastases were significantly more presented among the elderly patients (p = 0.032 ). Conclusions . The rate of cytological prediction to malignancy in elderly women is high. Tracheal compression is a common surgical indication in the elderly patients. The final diagnoses of malignancy predominate in elderly women. The oldest TM patients present a higher number of advanced thyroid tumors and distant metastases.