Synchronous Penile Metastasis from a High-Grade Adenocarcinoma of the Prostate. (16th October 2012)

• Record Type: Journal Article
• Authors: Dijkstra, S.; van der Heijden, A. G.; Schaafsma, H. E.; Mulders, P. F. A.
• Other Names: Hong S. K. Academic Editor.; Maffezzini M. Academic Editor.; Perachino M. Academic Editor.
• Is Part Of: Case reports in urology. Volume 2012(2012)
• Publication Date: 2012-10-16
• Subjects: Urology -- Periodicals; Urology -- Case studies -- Periodicals; Genitourinary organs -- Diseases -- Periodicals; Urologic Diseases; Genitourinary organs -- Diseases; Urology; Periodicals; Case studies; Periodicals; 616.6005
• DOI: 10.1155/2012/193787
• Languages: English
• ISSNs: 2090-696X

Abstract

Abstract : Metastasis to the glans penis is a rare phenomenon and usually occurs in a late stage of disease. A 68-year-old man was referred to our clinic because of two indurated lesions of the glans penis and minor lower urinary tract symptoms. Digital rectal examination revealed a hard nodular prostate, and serum prostate-specific antigen (sPSA) level was 13.3 ng/mL. Biopsies of the penile lesions and transrectal ultrasound-guided prostate biopsies were taken. Immunohistochemical staining of formalin-fixed paraffin-embedded tissue exposed a synchronous penile metastasis from a high-grade adenocarcinoma of the prostate. Except a pathologically enlarged lymph node detected with MRI there was no suspicion on other metastases. Currently this patient is being treated with a Gonadoreline (GnRH) antagonist. Nevertheless, the prognosis will be poor.